On “Incomplete” Anti-Rh Antibodies: Mechanism of Direct Agglutination Induced by Mercaptoethanol*

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On "incomplete" Anti-rh Antibodies: Mechanism of Direct Agglutination Induced by Mercaptoethanol.

Since "incomplete" or "blocking" antibodies were first demonstrated in 1944 (1, 2), a variety of techniques has been developed to demonstrate the combination of incomplete antibodies with the appropriate erythrocytes (3). These procedures utilize high protein media, enzyme-treated cells, the antiglobulin (Coombs') reaction, hypotonic environments, or isotopic labeling. Previous explanations for...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1965

ISSN: 0021-9738

DOI: 10.1172/jci105240